In the Hebrew year 2448 (1312 BCE), Miriam spoke negatively about her brother Moses, and was afflicted with the skin malady, tzarat. In his great humility, Moses then prayed for Miriam to be healed. God instructed that she be quarantined outside the Israelite camp for seven days. In testimony to their great love for Miriam, the entire Jewish nation waited during this period before journeying onward. (Numbers ch. 12)